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- MPS disease information
黏多醣儲積症疾病的背景資料 - How GAG accumulation affects cartilage
黏多醣體-葡萄糖胺聚合醣儲積如何影響軟骨 - Hip dysplasia in MPS
黏多醣儲積症引起的髖關節發育不良 - Spinal deformities in MPS
黏多醣儲積症引起的脊椎變異 - Ribs and shoulders in MPS
黏多醣儲積症引起的肋骨和肩膀問題 - Hand and other bone deformities in MPS
手和其他骨骼異常 - Non-skeletal manifestations of MPS
黏多醣儲積症其他非骨骼系統的表徵 - Diagnostic dilemma
診斷難題
首頁 >> 黏多醣的骨骼問題 >> Hand and other bone deformities in MPS >> Madelung’s-type deformity
Hand and other bone deformities in MPS
Madelung’s-type deformity1
- Madelung’s deformity is a wrist malformation typically seen in adolescent females
- The deformity may be characterized by ulnar protrusion(尺骨前突), wrist dislocation(腕關節脫臼), and/or radial hypoplasia
- It is usually associated with a mutation in the SHOX gene
- The hands of patients with MPS have a similar bent appearance to that seen in Madelung’s deformity and the term “Madelung’s-type deformity” is used to describe the hands of patients with MPS
- Munns C and Glass I. In: Pagon RA, Bird TD, Dolan CR, Stephens K, Adam MP, editors. GeneReviews™ Seattle (WA): University of Washington, Seattle; 1993–2008.
- Lachman R, et al. J Ped Rehabil Med 2010;3(2):109–118.
- Image courtesy of Klane K White.